Forschungsportal Sachsen-Anhalt
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RNA protein interactions coordinating gene expression and replication of hepatitis C virus

Projektbearbeiter:
Dipl. Biochem. Emanuel Ochs, Dipl. Biol. Susan Weinlich
Finanzierung:
Land (Sachsen-Anhalt) ;
The project aims at getting detailed insights into the molecular mechanisms that underlie the intracellular multiplication of the RNA genomes of the human pathogen hepatitis C virus (HCV). Specifically, we want to understand the role of a group of ubiquitous cellular factors, the so-called NF/NFAR proteins, in the coordination of the translation and replication process of the viral RNAs and to examine the impact of posttranslational modifications of the NF/NFAR proteins along their recruitment as functional components of the viral replication machinery.

Anmerkungen

Dieses Projekt wird im Rahmen der Exzellenzinitiative des Landes Sachsen-Anhalt in Kollaboration mit PD Dr. Antje Ostareck-Lederer und PD Dr. Dirk Ostareck durchgefuehrt.

Schlagworte

Hepatitis C virus

Kontakt

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