RNA protein interactions coordinating gene expression and replication of hepatitis C virus
Projektleiter:
Projektbearbeiter:
Dipl. Biochem. Emanuel Ochs,
Dipl. Biol. Susan Weinlich
Finanzierung:
Forschergruppen:
The project aims at getting detailed insights into the molecular mechanisms that underlie the intracellular multiplication of the RNA genomes of the human pathogen hepatitis C virus (HCV). Specifically, we want to understand the role of a group of ubiquitous cellular factors, the so-called NF/NFAR proteins, in the coordination of the translation and replication process of the viral RNAs and to examine the impact of posttranslational modifications of the NF/NFAR proteins along their recruitment as functional components of the viral replication machinery.
Anmerkungen
Dieses Projekt wird im Rahmen der Exzellenzinitiative des Landes Sachsen-Anhalt in Kollaboration mit PD Dr. Antje Ostareck-Lederer und PD Dr. Dirk Ostareck durchgefuehrt.
Schlagworte
Hepatitis C virus
Kontakt

Prof. Dr. Sven-Erik Behrens
Martin-Luther-Universität Halle-Wittenberg
Naturwissenschaftliche Fakultät I
Institut für Biochemie und Biotechnologie
Kurt-Mothes-Str. 3a
06120
Halle (Saale)
Tel.:+49 345 5524960
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