Prescription of tailored physical exercise from the intergration of omic, clinical and lifestyle data to prevent cardiovascular diseases

Research has shown that physical exercise is an effective therapeutic tool to deal with
cardiovascular diseases (CVDs). However, the success of these preventive programs depends
on the ability to identify the population at risk and to apply tailored physical exercise
interventions. The purpose of this project will be to integrate omic, clinical and lifestyle data to
define the cardiovascular risk level of an adult population to propose tailored physical exercise
programs that focuses on those physical condition factors most necessary for each person
according with their health status. A randomized representative sample of the population (men
and women) with ages between 18 and 65 years old will be selected. At a methodological level,
participants will be classified into several risk levels of suffering from CVDs and an initial
evaluation of inflammatory, protein, lipid, clinical and lifestyle markers will be made. Based on
this stratification, a tailored physical exercise intervention will be performed. Lastly, a final
evaluation will be made to analyze the effectiveness of the intervention in each of the defined
categories. We will try to carry out a "proof of concept" to evaluate the feasibility of our plan and
methodology to refine the proposal to improve it to subsequently participate in future European
calls (HORIZON, ERAPerMed, or MSCA schemes).