Sub-100 ps TOF CRT impact in interventional molecular brain imaging
Projektleiter:
Prof. Dr. Christoph Hoeschen , M.Sc. Knuth Scheiff
Finanzierung:
Haushalt;
Forschergruppen:
Time Of Flight (TOF) capability in PET imaging enhances Signal to Noise Ratio in inverse proportion to the temporal resolution. The Coincidence Resolving Time (CRT) in commercial PET scanners is about 500 ps (FWHM) but current technology limit approaches 10 ps CRT (FWHM) corresponding to 1.5 mm spatial resolution.
TOF increases lesion detection capability, the robustness of iterative reconstruction, and reduces bias in quantification through improved
attenuation, scatter, and random corrections. This investigation studies through simulations the possible enhancements in brain imaging of sub-100 ps CRT technology, in both static and dynamic brain studies.
We will develop prototyp PET detectors.
TOF increases lesion detection capability, the robustness of iterative reconstruction, and reduces bias in quantification through improved
attenuation, scatter, and random corrections. This investigation studies through simulations the possible enhancements in brain imaging of sub-100 ps CRT technology, in both static and dynamic brain studies.
We will develop prototyp PET detectors.
Anmerkungen
Kooperation mit Institute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH (DE)
und Nuevo Hospital La Fe-Valencia (ES)
Schlagworte
TOF PET, brain imaging, fast detectors
Geräte im Projekt
Kontakt
Prof. Dr. Christoph Hoeschen
Otto-von-Guericke-Universität Magdeburg
Fakultät für Elektrotechnik und Informationstechnik
Universitätsplatz 2
39106
Magdeburg
Tel.:+49 391 6718863
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