Die Rolle von non-kanonischen Poly(A)-Polymerasen für die Homöostase der Keimbahn

Our broad goal is to understand animal tissue development and pathology at the level of cytoplasmic gene expression regulation. We are particularly interested in the function of non-canonical poly(A) polymerases that modify mRNA molecules at their 3 ends and thereby control biological processes as diverse as cellular senescence, stress response, and gametogenesis.