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SulfoSys: Sulfolobus Systems Biology: Exploiting the hot archaeal metabolic potential for Biotechnology
Sofia Figueiredo
Archaea harbor a unique metabolism, which is characterized by many new unusual enzymes and pathways. Archaeal genome sequencing reveals up to 50% of hypotheticals/proteins of unknown function and many homologs of common bacterial and eukaryotic metabolic enzymes are missing. Most current classical studies address only single unusual archaeal enzymes and in only very few cases complete pathways were analyzed. Therefore, the fascinating complexity of archaeal metabolism and also its regulation is still far from being understood and in respect to natural microbial biodiversity the third domain of Life the Archaea− is not commercially exploited so far.


Archae, Systembiologie

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