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Effect of vascular dysregulation in glaucomatous vision restoration
Wanshu Zhou
Hypothesis: Mental stress can cause vascular dysregulation (unregulated vascular diameter, flow velocity, and vessel dynamics) in the brain and retina, and an impaired dynamic vessel response will prevent vision restoration that can be induced by transorbital alternating current stimulation (tACS). By correlating the dynamic vessel response (vascular dysregulation, VDR) and stress levels in patients and studying their influence on the degree of vision recovery in glaucoma patients, We hope to uncover if patients with a regulated vascular response can recover their vision while those with vascular dysregulation cannot. This study will help to better understand and treat optic nerve damage, for example after glaucoma, or optic neuropathy and vision loss (hemianopia) after stroke.

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