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Cluster 1: Tackling diseases (2021), 7 calls open
In this work programme, destination 3 will focus on major societal challenges linked to the Commission's political priorities such as the fight against cancer and other non-communicable diseases, better diagnosis and treatment of rare diseases, preparedness and response to and surveillance of health threats and epidemics, reduction of the number of antimicrobial-resistant infections, improving vaccination rates, demographic change, mental health and digital empowerment in health literacy. In particular, the topics under this destination will support activities aiming at: i) better understanding of diseases, their drivers and consequences, including pain and the causative links between health determinants and diseases, and better evidence-base for policy-making; ii) better methodologies and diagnostics that allow timely and accurate diagnosis, identification of personalised treatment options and assessment of health outcomes, including for patients with a rare disease; iii) development and validation of effective intervention for better surveillance, prevention, detection, treatment and crisis management of infectious disease threats; iv) innovative health technologies developed and tested in clinical practice, including personalised medicine approaches and use of digital tools to optimise clinical workflows; v) new and advanced therapies for non-communicable diseases, including rare diseases developed in particular for those without approved options, supported by strategies to make them affordable for the public payer; and vi) scientific evidence for improved/tailored policies and legal frameworks and to inform major policy initiatives at global level (e.g. WHO Framework Convention on Tobacco Control; UNEA Pollution Implementation Plan).

Under this destination the EU has published seven calls for proposals that are open for admission:

1. Improved supportive, palliative, survivorship and end-of-life care of cancer patients (HORIZON-HLTH-2021-DISEASE-04-01)
2. Building a European innovation platform for the repurposing of medicinal products (HORIZON-HLTH-2021-DISEASE-04-02)
3. Innovative approaches to enhance poverty-related diseases research in sub-Saharan Africa (HORIZON-HLTH-2021-DISEASE-04-03)
4. Clinical validation of artificial intelligence (AI) solutions for treatment and care (HORIZON-HLTH-2021-DISEASE-04-04)
5. A roadmap towards the creation of the European partnership on One Health antimicrobial resistance (OH AMR) (HORIZON-HLTH-2021-DISEASE-04-05)
6. Building a European partnership for pandemic preparedness (HORIZON-HLTH-2021-DISEASE-04-06)
7. Personalised medicine and infectious diseases: understanding the individual host response to viruses (e.g. SARS-CoV-2) (HORIZON-HLTH-2021-DISEASE-04-07)

Further Information: